SOFA 评分SOFA Score

序贯器官衰竭评估 · 每24小时取最差值Sequential Organ Failure Assessment · worst value per 24h

1呼吸系统Respiratory0

氧合方式Oxygenation input

PaO₂/FiO₂（有血气）PaO2/FiO2 (ABG) SpO₂/FiO₂（无血气估算）SpO2/FiO2 (no ABG, estimated)

正在接受呼吸支持（有创机械通气/CPAP等）— 影响3–4分的判定On respiratory support (invasive ventilation/CPAP) — required for scores 3–4

2凝血系统Coagulation0

血小板（×10⁹/L）Platelets (×10⁹/L)

3肝脏Liver0

总胆红素（mg/dL）Total Bilirubin (mg/dL)

1 mg/dL = 17.1 µmol/L

4循环系统Cardiovascular0

平均动脉压 MAP（mmHg）Mean Arterial Pressure (mmHg)

血管活性药物剂量（µg/kg/min，持续≥1小时）— 留空表示未使用Vasopressor dose (µg/kg/min, ≥1h) — leave blank if not used

使用多巴酚丁胺（任意剂量）Dobutamine (any dose)

5中枢神经系统Central Nervous System0

GCS 总分（3–15）GCS total (3–15)

6肾脏Renal0

肌酐（mg/dL）Creatinine (mg/dL)

24小时尿量（mL，选填）24h urine output (mL, optional)

取肌酐分与尿量分中较高者Uses whichever of creatinine/urine-output gives the higher score

SOFA 总分（0–24）Total SOFA (0–24)

解读要点：SOFA 最初用于描述器官功能障碍程度，而非直接的死亡率预测工具；不同队列研究得出的"分数—死亡率"对应关系差异较大（如总分>15时约90%住院死亡率，来自 Ferreira 2001 JAMA），本工具不提供逐分对应的死亡率细表以免误导。
按 Sepsis-3 标准：在可疑感染背景下，SOFA 较基线上升 ≥2 分即提示新发器官功能障碍；若无已知基础器官功能障碍，基线默认为0分。建议连续监测评分变化趋势，而非仅看单次绝对值。 Interpretation: SOFA was originally designed to describe organ dysfunction, not to precisely predict mortality — published score-to-mortality mappings vary meaningfully between cohorts (e.g. >15 ≈ 90% hospital mortality, Ferreira 2001 JAMA); this tool intentionally omits a granular per-point mortality table to avoid over-precision.
Per Sepsis-3: in the setting of suspected infection, a SOFA increase of ≥2 points from baseline indicates new organ dysfunction (assume baseline = 0 if no known prior dysfunction). Trend over serial measurements matters more than a single absolute value.